EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.5.4.12 | dAMP | at low substrate, dCMP, concentration: activation at higher concentration of either: inhibition | Equus asinus | |
3.5.4.12 | dCTP | allosteric activator | Equus asinus | |
3.5.4.12 | dCTP | allosteric activator, increases substrate affinity | Equus asinus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.5.4.12 | dAMP | at low substrate, dCMP, concentration: activation at higher concentration of either: competitive inhibition; competitive inhibitor, activates enzyme at low substrate concentration mimicing the cooperative effect of the substrate | Equus asinus | |
3.5.4.12 | dTTP | allosteric inhibitor | Equus asinus | |
3.5.4.12 | dUMP | competitive inhibition, kinetics and mechanism of inhibition | Equus asinus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.5.4.12 | additional information | - |
additional information | kinetic studies, steady-state kinetics, allosteric kinetics | Equus asinus | |
3.5.4.12 | 0.024 | - |
dCMP | in the presence of dCTP | Equus asinus | |
3.5.4.12 | 0.037 | - |
dCMP | in the presence of dCTP | Equus asinus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.5.4.12 | 120000 | - |
- |
Equus asinus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.12 | dCMP + H2O | Equus asinus | - |
dUMP + NH3 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.5.4.12 | Equus asinus | - |
donkey | - |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
3.5.4.12 | dCMP + H2O = dUMP + NH3 | mechanism | Equus asinus | |
3.5.4.12 | dCMP + H2O = dUMP + NH3 | regulation, allosteric end-product regulation | Equus asinus | |
3.5.4.12 | dCMP + H2O = dUMP + NH3 | highly regulated allosteric enzyme | Equus asinus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.5.4.12 | spleen | - |
Equus asinus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.5.4.12 | dCMP + H2O | - |
Equus asinus | dUMP + NH3 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.5.4.12 | hexamer | 6 identical subunits | Equus asinus |