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Literature summary extracted from

  • Ikai, H.; Yamamoto, S.
    Two genes involved in the 1,3-diaminopropane production pathway in Haemophilus influenzae (1998), Biol. Pharm. Bull., 21, 170-173.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.6.1.76 medicine
-
 Acinetobacter baumannii
2.6.1.76 medicine responsible for many human infections including otitis media, meningitis, epiglottis and pneumonia Haemophilus influenzae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.6.1.76 Escherichia coli clone carrying the dat homolog of H. influenzae Haemophilus influenzae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.76 49400
-
 predicted from amino acid sequence, gene HI0949 Haemophilus influenzae
2.6.1.76 56200
-
 predicted from amino acid sequence, gene HI946 Haemophilus influenzae

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.76 Acinetobacter baumannii
-
-
-
2.6.1.76 Haemophilus influenzae
-
 Rd, types a, b, d, e, f
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.6.1.76 L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate Involved in the formation of 1,3-diaminopropane in Haemophilus influenzae and Acinetobacter baumannii. A product of the ddc gene that also encodes L-2,4-diaminobutyrate decarboxylase in Acinetobacter baumannii. Differs from EC 2.6.1.46 diaminobutyrate-pyruvate transaminase, which has pyruvate as the amino-group acceptor Acinetobacter baumannii
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.76 L-2,4-diaminobutyric acid + 2-oxoglutaric acid
-
 Haemophilus influenzae L-glutamic acid + L-aspartic beta-semialdehyde
-
 ?
2.6.1.76 L-2,4-diaminobutyric acid + 2-oxoglutaric acid
-
 Acinetobacter baumannii L-glutamic acid + L-aspartic beta-semialdehyde
-
 r
2.6.1.76 L-glutamic acid + L-aspartic beta-semialdehyde
-
 Haemophilus influenzae L-2,4-diaminobutyric acid + 2-oxoglutaric acid
-
 ?
2.6.1.76 L-glutamic acid + L-aspartic beta-semialdehyde
-
 Acinetobacter baumannii L-2,4-diaminobutyric acid + 2-oxoglutaric acid
-
 r