EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.268 | 2-(R)-hydroxypropyl-CoM + NAD+ | Xanthobacter sp. | - |
2-oxopropyl-CoM + NADH | - |
? | |
1.1.1.268 | 2-(R)-hydroxypropyl-CoM + NAD+ | Xanthobacter sp. Py2 | - |
2-oxopropyl-CoM + NADH | - |
? | |
1.8.1.5 | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | Xanthobacter sp. | involved in epoxide carboxylation pathway in bacteria, reverse reaction more important | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
r | |
1.8.1.5 | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | Xanthobacter sp. Py2 | involved in epoxide carboxylation pathway in bacteria, reverse reaction more important | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
r | |
4.4.1.23 | epoxypropane + HS-CoM | Xanthobacter autotrophicus | this enzyme forms component I of a four-component enzyme system, comprising EC 4.2.99.19 2-hydroxypropyl-CoM lyase, component I, EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating), component II, EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase, component II and EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase, component IV that is involved in epoxyalkane carboxylation | 2-hydroxypropyl-CoM | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.268 | Xanthobacter sp. | - |
- |
- |
1.1.1.268 | Xanthobacter sp. Py2 | - |
- |
- |
1.8.1.5 | Xanthobacter sp. | - |
Py2 | - |
1.8.1.5 | Xanthobacter sp. Py2 | - |
Py2 | - |
4.4.1.23 | Xanthobacter autotrophicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.268 | cell culture | - |
Xanthobacter sp. | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.268 | 2-(R)-hydroxypropyl-CoM + NAD+ | - |
Xanthobacter sp. | 2-oxopropyl-CoM + NADH | - |
? | |
1.1.1.268 | 2-(R)-hydroxypropyl-CoM + NAD+ | - |
Xanthobacter sp. Py2 | 2-oxopropyl-CoM + NADH | - |
? | |
1.8.1.5 | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
Xanthobacter sp. | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | - |
r | |
1.8.1.5 | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
Xanthobacter sp. Py2 | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | - |
r | |
1.8.1.5 | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | dual function enzyme, reverse reaction of component II of carboxylation pathway | Xanthobacter sp. | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
r | |
1.8.1.5 | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | involved in epoxide carboxylation pathway in bacteria, reverse reaction more important | Xanthobacter sp. | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
r | |
1.8.1.5 | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | dual function enzyme, reverse reaction of component II of carboxylation pathway | Xanthobacter sp. Py2 | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
r | |
1.8.1.5 | 2-mercaptoethanesulfonate + acetoacetate + NADP+ | involved in epoxide carboxylation pathway in bacteria, reverse reaction more important | Xanthobacter sp. Py2 | 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+ | - |
r | |
4.4.1.23 | epoxypropane + HS-CoM | catalyzes the reaction of CoM with R-epoxypropane at a rate approximately twice of that with S-epoxypropane | Xanthobacter autotrophicus | 2-hydroxypropyl-CoM | - |
? | |
4.4.1.23 | epoxypropane + HS-CoM | this enzyme forms component I of a four-component enzyme system, comprising EC 4.2.99.19 2-hydroxypropyl-CoM lyase, component I, EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating), component II, EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase, component II and EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase, component IV that is involved in epoxyalkane carboxylation | Xanthobacter autotrophicus | 2-hydroxypropyl-CoM | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.4.1.23 | More | this enzyme forms component I of a four-component enzyme system, comprising EC 4.2.99.19 2-hydroxypropyl-CoM lyase, component I, EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating), component II, EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase, component II and EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase, component IV that is involved in epoxyalkane carboxylation | Xanthobacter autotrophicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.268 | 2-mercaptoethanesulfonate | i.e. coenzyme M: function in catabolic pathway of hydrocarbon oxidation | Xanthobacter sp. | |
1.1.1.268 | NAD+ | - |
Xanthobacter sp. | |
1.8.1.5 | 2-mercaptoethanesulfonic acid | coenzyme M | Xanthobacter sp. | |
1.8.1.5 | FAD | enzyme bound | Xanthobacter sp. |