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Literature summary extracted from

  • Misset-Smits, M.; van Ophem, P.W.; Sakuda, S.; Duine, J.A.
    Mycothiol, 1-O-(2'-[N-acwtyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol, is the factor of NAD/factor-dependent formaldehyde dehydrogenase (1997), FEBS Lett., 409, 221-222.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.306 acetaldehyde
-
 Amycolatopsis methanolica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.306 formaldehyde + 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol + NAD+ Rhodococcus erythropolis
-
 S-formylmycothiol + NADH
-
 ?
1.1.1.306 formaldehyde + 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol + NAD+ Amycolatopsis methanolica
-
 S-formylmycothiol + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.306 Amycolatopsis methanolica
-
-
-
1.1.1.306 Rhodococcus erythropolis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.306 cell culture
-
 Rhodococcus erythropolis
-
1.1.1.306 cell culture
-
 Amycolatopsis methanolica
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.306 0.23
-
-
 Amycolatopsis methanolica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.306 formaldehyde + 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol + NAD+
-
 Rhodococcus erythropolis S-formylmycothiol + NADH
-
 ?
1.1.1.306 formaldehyde + 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol + NAD+
-
 Amycolatopsis methanolica S-formylmycothiol + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.306 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol mycothiol Rhodococcus erythropolis
1.1.1.306 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol mycothiol Amycolatopsis methanolica
1.1.1.306 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol high specificity for mycothiol Rhodococcus erythropolis
1.1.1.306 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D-myo-inositol high specificity for mycothiol Amycolatopsis methanolica
1.1.1.306 NAD+
-
 Rhodococcus erythropolis
1.1.1.306 NAD+
-
 Amycolatopsis methanolica