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Literature summary extracted from

  • Connors, M.A.; Barnsley, E.A.
    Metabolism of naphthalene by pseudomonads: Salicylaldehyde as the first possible inducer in the metabolic pathway (1980), J. Bacteriol., 141, 1052-1054.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.65 mutant strains, lacking induction of enzyme synthesis by naphthalene growth media Pseudomonas sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.65 salicylaldehyde + NAD+ + H2O Pseudomonas sp.
-
salicylate + NADH
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.65 Pseudomonas sp.
-
strain ATCC 17483
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.65 cell culture inducible enzyme synthesis only by growth in succinate- and naphthalene-containing media, first inducer for enzyme synthesis of the naphthalene catabolism is salicylaldehyde Pseudomonas sp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.65 0.89
-
wild type naphthalene-succinate grown cells Pseudomonas sp.
1.2.1.65 118
-
mutant strain MC4, 2-aminobenzoate induced cells Pseudomonas sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.65 salicylaldehyde + NAD+ + H2O
-
Pseudomonas sp. salicylate + NADH
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.65 NAD+
-
Pseudomonas sp.