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Literature summary extracted from

  • Inui, H.; Miyatake, K.; Nakano, Y.; Kitaoka, S.
    Pyruvate: NADP+ oxidoreductase from Euglena gracilis: the kinetic properties of the enzyme (1989), Arch. Biochem. Biophys., 274, 434-442.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.51 2',5'-ADP
-
 Euglena gracilis
1.2.1.51 2',5'-ATP-ribose
-
 Euglena gracilis
1.2.1.51 CO2 product inhibition Euglena gracilis
1.2.1.51 Quinacrine
-
 Euglena gracilis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.51 additional information
-
 additional information kinetic mechanism Euglena gracilis
1.2.1.51 0.0066
-
 CoA with NADP+ Euglena gracilis
1.2.1.51 0.0081
-
 CoA with methyl viologen Euglena gracilis
1.2.1.51 0.027
-
 pyruvate with NADP+ Euglena gracilis
1.2.1.51 0.028
-
 NADP+
-
 Euglena gracilis
1.2.1.51 0.033
-
 pyruvate with methyl viologen Euglena gracilis
1.2.1.51 0.068
-
 methyl viologen
-
 Euglena gracilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.51 pyruvate + CoA + NADP+ Euglena gracilis
-
 acetyl-CoA + CO2 + NADPH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.51 Euglena gracilis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.51
-
 Euglena gracilis

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.51 15.3
-
-
 Euglena gracilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.51 pyruvate + CoA + methyl viologen
-
 Euglena gracilis acetyl-CoA + CO2 + reduced methyl viologen
-
 r
1.2.1.51 pyruvate + CoA + NADP+
-
 Euglena gracilis acetyl-CoA + CO2 + NADPH
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.51 NADP+ not NAD+ Euglena gracilis