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Literature summary extracted from

  • Maruyama, K.
    Isolation and identification of the reaction product of alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase (1979), J. Biochem., 86, 1671-1677.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.312 additional information Pseudomonas straminea 2-pyrone-4,6-dicarboxylic acid may be a metabolic intermediate in the bacterial metabolism of protocatechuic acid ?
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?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.312 Pseudomonas straminea
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-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.312 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+
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Pseudomonas straminea 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH following intramolecular dehydrogenation to the lactone 2-pyrone-4,6-dicarboxylic acid ?
1.1.1.312 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+
-
Pseudomonas straminea 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH it is not clear whether the lactonization occurs enzymatically or nonenzymatically ?
1.1.1.312 additional information 2-pyrone-4,6-dicarboxylic acid may be a metabolic intermediate in the bacterial metabolism of protocatechuic acid Pseudomonas straminea ?
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.312 NADP+
-
Pseudomonas straminea