EC Number | Cloned (Comment) | Organism |
---|---|---|
1.2.1.31 | two genes, lys1+ and lys7+ are required for the synthesis of the enzyme, some regions of the enzyme sequence are similar to the sequence of Saccharomyces cerevisiae, e.g. Schizosaccharomyces pombe enzyme residues 345 through 385, and 449 through 470 | Schizosaccharomyces pombe |
1.2.1.95 | - |
Schizosaccharomyces pombe |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.31 | L-lysine | 20% inhibition at 50 mM | Saccharomyces cerevisiae | |
1.2.1.31 | L-lysine | 54% inhibition at 1 mM and 80% inhibition at 4 mM | Schizosaccharomyces pombe | |
1.2.1.95 | L-lysine | enzyme from Schizosaccharomyces pombe is more sensitive to feedback inhibition by lysine in vitro than the enzyme of Saccharomyces cerevisiae | Schizosaccharomyces pombe |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.31 | Saccharomyces cerevisiae | - |
- |
- |
1.2.1.31 | Schizosaccharomyces pombe | - |
- |
- |
1.2.1.95 | Schizosaccharomyces pombe | P40976 | - |
- |
1.2.1.95 | Schizosaccharomyces pombe 972 | P40976 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.31 | L-2-aminoadipate + NADPH | in presence of ATP + Mg2+ | Saccharomyces cerevisiae | L-2-aminoadipate 6-semialdehyde + NADP+ + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.2.1.95 | Lys1+ | - |
Schizosaccharomyces pombe |
EC Number | Organism | Comment | Expression |
---|---|---|---|
1.2.1.95 | Schizosaccharomyces pombe | activity from cells grown in lysine-supplemented minimal or YEPD media is less than the activity of cells grown in minimal medium | additional information |