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Literature summary extracted from
- Plant succinic semialdehyde dehydrogenase. Cloning, purification, localization in mitochondria, and regulation by adenine nucleotides (1999), Plant Physiol., 121, 589-597.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.2.1.24 | - |
Arabidopsis sp. |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.1.24 | 4-hydroxybenzaldehyde | 10 mM, 82% inhibition | Arabidopsis sp. |  |
| 1.2.1.24 | ADP | - |
Arabidopsis sp. | |
| 1.2.1.24 | AMP | - |
Arabidopsis sp. | |
| 1.2.1.24 | ATP | - |
Arabidopsis sp. | |
| 1.2.1.24 | NADH | competitive with respect to NAD+ | Arabidopsis sp. | |
| 1.2.1.24 | pyridoxal 5'-phosphate | 10 mM, 25% inhibition | Arabidopsis sp. | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.2.1.24 | 0.13 | - |
NAD+ | - |
Arabidopsis sp. | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.2.1.24 | mitochondrion | matrix | Arabidopsis sp. | 5739 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.24 | 53000 | - |
x * 53000, SDS-PAGE | Arabidopsis sp. |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.2.1.24 | Arabidopsis sp. | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.2.1.24 | - |
Arabidopsis sp. |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.24 | additional information | - |
- |
Arabidopsis sp. |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.1.24 | succinate semialdehyde + NAD+ + H2O | - |
Arabidopsis sp. | succinate + NADH | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.2.1.24 | ? | x * 53000, SDS-PAGE | Arabidopsis sp. |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.24 | 9 | 9.5 | - |
Arabidopsis sp. |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.1.24 | NAD+ | - |
Arabidopsis sp. | |
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Release 2023.1 (January 2023)
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