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Literature summary extracted from

  • Yamaura, I.; Matsumoto, T.; Funatsu, M.; Shinohara, T.
    Purification and some properties of succinic semialdehyde dehydrogenase from barley seeds (1988), Agric. Biol. Chem., 52, 2929-2930.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.24 5,5'-dithiobis(2-nitrobenzoic acid)
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 Cu2+
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 Fe3+
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 Hg2+
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 Pb2+
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 PCMB
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 Zn2+
-
 Hordeum vulgare subsp. vulgare

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.24 0.0159
-
 succinate semialdehyde
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 0.166
-
 NAD+
-
 Hordeum vulgare subsp. vulgare

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.24 60000
-
 4 * 60000, SDS-PAGE Hordeum vulgare subsp. vulgare
1.2.1.24 225000
-
 gel filtration Hordeum vulgare subsp. vulgare

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.24 Hordeum vulgare subsp. vulgare
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.24
-
 Hordeum vulgare subsp. vulgare

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.24 seed
-
 Hordeum vulgare subsp. vulgare
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.24 269
-
-
 Hordeum vulgare subsp. vulgare

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.24 succinate semialdehyde + NAD+ + H2O
-
 Hordeum vulgare subsp. vulgare succinate + NADH
-
 ?
1.2.1.24 succinate semialdehyde + NADP+ + H2O reduction rate is only a few percent of that of NAD+ Hordeum vulgare subsp. vulgare succinate + NADPH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.24 tetramer 4 * 60000, SDS-PAGE Hordeum vulgare subsp. vulgare

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.2.1.24 42
-
-
 Hordeum vulgare subsp. vulgare

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.2.1.24
-
 40 pH 8.9, 10 min, stable Hordeum vulgare subsp. vulgare

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.1.24 9
-
-
 Hordeum vulgare subsp. vulgare

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.2.1.24 7 9 4°C, 18 h, stable Hordeum vulgare subsp. vulgare

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.24 NAD+
-
 Hordeum vulgare subsp. vulgare
1.2.1.24 NADP+ cofactor Hordeum vulgare subsp. vulgare
1.2.1.24 NADP+ reduction rate is only a few percent of that of NAD+ Hordeum vulgare subsp. vulgare