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Literature summary extracted from

  • Caballero, E.; Baldoma, L.; Ros, J.; Boronat, A.; Aguilar, J.
    Identification of lactaldehyde dehydrogenase and glycolaldehyde dehydrogenase as functions of the same protein in Escherichia coli (1983), J. Biol. Chem., 258, 7788-7792.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.22 (S)-lactaldehyde + NAD+ Escherichia coli aerobic metabolism of fucose (S)-lactate + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.21 Escherichia coli
-
-
-
1.2.1.22 Escherichia coli
-
 lactaldehyde dehydrogenase and glycolaldehyde dehydrogenase are functions of the same protein
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.21 protein identical to lactaldehyde dehydrogenase Escherichia coli
1.2.1.22
-
 Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.21 0.01
-
 enzyme activity in crude extracts of temperature sensitive strain JA-104 at 42°C Escherichia coli
1.2.1.21 0.12
-
 enzyme activity in crude extracts of temperature sensitive strain JA-104 at 30°C Escherichia coli
1.2.1.21 0.13
-
 enzyme activity in crude extracts of strain 1 grown on casein hydrosylate Escherichia coli
1.2.1.21 0.21
-
 enzyme activity in crude extracts of strain 1 grown on fucose Escherichia coli
1.2.1.21 0.34
-
 enzyme activity in crude extracts of strain JA-102 grown on ethylene glycol Escherichia coli
1.2.1.21 10.5
-
 strain 3 Escherichia coli
1.2.1.21 30.5
-
 strain JA-102 Escherichia coli
1.2.1.22 6.4
-
 strain 3 Escherichia coli
1.2.1.22 17
-
 strain JA-102 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.21 glycolaldehyde + NAD+ + H2O
-
 Escherichia coli glycolate + NADH
-
 ?
1.2.1.22 (S)-lactaldehyde + NAD+ aerobic metabolism of fucose Escherichia coli (S)-lactate + NADH
-
 ?
1.2.1.22 (S)-lactaldehyde + NAD+ + H2O
-
 Escherichia coli (S)-lactate + NADH + H+
-
 ?
1.2.1.22 glycolaldehyde + NAD+ + H2O
-
 Escherichia coli glycolate + NADH
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.2.1.22 25
-
 assay at Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.22 NAD+
-
 Escherichia coli