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Literature summary extracted from

  • Gutheil, W.G.; Kasimoglu, E.; Nicholson, P.C.
    Induction of glutathione-dependent formaldehyde dehydrogenase activity in Escherichia coli and Hemophilus influenza (1997), Biochem. Biophys. Res. Commun., 238, 693-696.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.284 formaldehyde + glutathione + NAD+ Haemophilus influenzae inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ Escherichia coli inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment S-formylglutathione + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.284 Escherichia coli
-
-
-
1.1.1.284 Haemophilus influenzae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.284 formaldehyde + glutathione + NAD+
-
 Haemophilus influenzae S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+
-
 Escherichia coli S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment Haemophilus influenzae S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ inducible enzyme, at least one function of the enzyme in Gram-negative bacteria is to detoxify exogenous formaldehyde encountered in their environment Escherichia coli S-formylglutathione + NADH + H+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.284 NAD+
-
 Haemophilus influenzae
1.1.1.284 NAD+
-
 Escherichia coli