EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.284 | 12-oxododecanoic acid | substrate inhibition | Homo sapiens | |
1.1.1.284 | NAD+ | product inhibition | Homo sapiens | |
1.1.1.284 | NADH | product inhibition | Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.284 | Zinc | zinc-dependent enzyme | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.284 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.284 | - |
Homo sapiens |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.1.1.284 | S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+ | random bi-bi mechanism for oxidation of S-hydroxymethylglutathione and 12-hydroxydodecanoic acid | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.284 | 12-hydroxydodedecanoic acid + glutathione + NAD+ | - |
Homo sapiens | 12-oxododecanoic acid + ? | - |
? | |
1.1.1.284 | formaldehyde + glutathione + NAD+ | the true substrate is a hemimercaptal, S-hydroxymethylglutathione, spontaneously formed from formaldehyde and glutathione | Homo sapiens | S-formylglutathione + NADH + H+ | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.284 | 0.217 | - |
12-Hydroxydodecanoic acid | - |
Homo sapiens | |
1.1.1.284 | 0.217 | - |
NAD+ | reaction with 12-hydroxydodecanoic acid | Homo sapiens | |
1.1.1.284 | 1.04 | - |
NAD+ | - |
Homo sapiens | |
1.1.1.284 | 1.04 | - |
S-hydroxymethyl glutathione | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.284 | NAD+ | - |
Homo sapiens |