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Literature summary extracted from

  • Van Ophem, P.W.; Duine, J.A.
    NAD- and co-substrate (GSH or factor)-dependent formaldehyde dehydrogenases from methylotrophic microorganisms act as a class III alcohol dehydrogenase (1994), FEMS Microbiol. Lett., 116, 87-93.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.284 formaldehyde + glutathione + NAD+ Paracoccus denitrificans principal enzyme for biological formaldehyde oxidation S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ [Candida] boidinii principal enzyme for biological formaldehyde oxidation S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ Ogataea angusta principal enzyme for biological formaldehyde oxidation S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ Paracoccus versutus principal enzyme for biological formaldehyde oxidation S-formylglutathione + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.284 Ogataea angusta
-
 alcohol dehydrogenase III
-
1.1.1.284 Paracoccus denitrificans
-
 alcohol dehydrogenase III
-
1.1.1.284 Paracoccus versutus
-
 alcohol dehydrogenase III
-
1.1.1.284 [Candida] boidinii
-
 alcohol dehydrogenase III
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.284 formaldehyde + glutathione + NAD+
-
 Paracoccus denitrificans S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+
-
 [Candida] boidinii S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+
-
 Ogataea angusta S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+
-
 Paracoccus versutus S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ principal enzyme for biological formaldehyde oxidation Paracoccus denitrificans S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ principal enzyme for biological formaldehyde oxidation [Candida] boidinii S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ principal enzyme for biological formaldehyde oxidation Ogataea angusta S-formylglutathione + NADH + H+
-
 ?
1.1.1.284 formaldehyde + glutathione + NAD+ principal enzyme for biological formaldehyde oxidation Paracoccus versutus S-formylglutathione + NADH + H+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.284 8
-
-
 Paracoccus denitrificans
1.1.1.284 8
-
-
 [Candida] boidinii
1.1.1.284 8
-
-
 Ogataea angusta
1.1.1.284 8
-
-
 Paracoccus versutus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.284 NAD+
-
 Paracoccus denitrificans
1.1.1.284 NAD+
-
 [Candida] boidinii
1.1.1.284 NAD+
-
 Ogataea angusta
1.1.1.284 NAD+
-
 Paracoccus versutus