Literature summary extracted from

Strittmatter, P.; Ball, E.G.
Formaldehyde dehydrogenase, a glutathione-dependent enzyme system (1955), J. Biol. Chem., 213, 445-461.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.284	Bos taurus	-	-	-
1.1.1.284	Gallus gallus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.284	liver	-	Gallus gallus	-
1.1.1.284	liver	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.284	formaldehyde + glutathione + NAD+	-	Gallus gallus	S-formylglutathione + NADH + H+	-	?
1.1.1.284	formaldehyde + glutathione + NAD+	-	Bos taurus	S-formylglutathione + NADH + H+	-	?

Temperature Stability [°C]

EC Number	Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
1.1.1.284	72	-	5 min, complete inactivation	Bos taurus

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.1.1.284	7.9	8.2	-	Bos taurus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.284	NAD+	-	Gallus gallus
1.1.1.284	NAD+	-	Bos taurus

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Release 2023.1 (January 2023)