Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Silverman, R.B.; Nandi, D.L.
    Effect of N-ethylmaleimide on beef and rat liver vitamin K1 epoxide reductase (1990), J. Enzyme Inhib., 3, 289-294.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.4.4 N-ethylmaleimide protected by vitamin K 2,3-epoxide Bos taurus
1.17.4.4 N-ethylmaleimide
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.17.4.4 microsome integral membrane protein Rattus norvegicus
-
-
1.17.4.4 microsome integral membrane protein Bos taurus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.17.4.4 Bos taurus
-
-
-
1.17.4.4 Rattus norvegicus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.17.4.4 phylloquinone + a protein with a disulfide bond + H2O = 2,3-epoxyphylloquinone + a protein with reduced L-cysteine residues ping-pong mechanism Bos taurus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.4.4 liver
-
 Rattus norvegicus
-
1.17.4.4 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.4.4 vitamin K 2,3-epoxide + dithiothreitol
-
 Rattus norvegicus vitamin K + oxidized dithiothreitol
-
 ?
1.17.4.4 vitamin K 2,3-epoxide + dithiothreitol
-
 Bos taurus vitamin K + oxidized dithiothreitol
-
 ?