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Literature summary extracted from

  • Fukuda, H.; Kawakami, Y.; Nakamura, S.
    A method to screen anticholesterol substances produced by microbes and a new cholesterol oxidase produced by Streptomyces violascens (1973), Chem. Pharm. Bull., 21, 2057-2060.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.3.6 cholesterol + O2 Streptomyces violascens
-
cholest-5-en-3-one + H2O2
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.3.6 Streptomyces violascens
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.3.6 cholesterol + O2 = cholest-5-en-3-one + H2O2 bifunctional enzyme, catalyzes both the oxidation of DELTA5-ene-3beta hydroxysteroids with a trans A-B ring junction to the corresponding DELTA5-3-ketosteroid with the reduction of oxygen to hydrogen peroxide, and the isomerization to the DELTA4-3-ketosteroid Streptomyces violascens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.3.6 cholesterol + O2
-
Streptomyces violascens cholest-4-en-3-one + H2O2
-
?
1.1.3.6 cholesterol + O2
-
Streptomyces violascens cholest-5-en-3-one + H2O2
-
?