EC Number | Crystallization (Comment) | Organism |
---|---|---|
1.1.1.95 | - |
Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.95 | amino acids | - |
Escherichia coli | |
1.1.1.95 | L-serine | allosteric inhibition, regulates the pathway of serine biosynthesis by end product inhibition interacting with His344, Asn346 and Asn364 | Escherichia coli |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.1.1.95 | 44000 | - |
4 * 44000, SDS-PAGE, each subunit is divided into 3 separate domains | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.95 | 3-phosphoglycerate + NAD+ | Escherichia coli | allosteric inhibition by L-serine, L-serine regulates the pathway of serine biosynthesis by end product inhibition interacting with His344, Asn346 and Asn364, 1 serine binds per subunit | 3-phosphohydroxypyruvate + NADH | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.95 | Escherichia coli | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.1.1.95 | 3-phospho-D-glycerate + NAD+ = 3-phosphooxypyruvate + NADH + H+ | regulation model with effector L-serine, member of the D-2-hydroxyacid dehydrogenases, D-isomer substrate specific, overview of related enzymes from other species | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.95 | 3-phosphoglycerate + NAD+ | - |
Escherichia coli | 3-phosphohydroxypyruvate + NADH | - |
r | |
1.1.1.95 | 3-phosphoglycerate + NAD+ | allosteric inhibition by L-serine, L-serine regulates the pathway of serine biosynthesis by end product inhibition interacting with His344, Asn346 and Asn364, 1 serine binds per subunit | Escherichia coli | 3-phosphohydroxypyruvate + NADH | - |
r |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.1.1.95 | More | subunit structure with substrate binding domain, coenzyme binding domain and regulatory domain, active sites | Escherichia coli |
1.1.1.95 | tetramer | 4 * 44000, SDS-PAGE, each subunit is divided into 3 separate domains | Escherichia coli |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.95 | NAD+ | - |
Escherichia coli | |
1.1.1.95 | NADH | - |
Escherichia coli |