Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Haeseleer, F.; Huang, J.; Lebiodas, L.; Saari, J.C.; Palczewski, K.
    Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal (1998), J. Biol. Chem., 273, 21790-21799.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.300 full-length short-chain dehydrogenase/reductase cDNA expressed in Escherichia coli, truncated cDNA expressed in SF9 insect cells, enzyme belongs to the short-chain dehydrogenase/reductase superfamily Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.300 all-trans-retinal + NADPH + H+ Homo sapiens
-
 all-trans-retinol + NADP+
-
 r
1.1.1.300 all-trans-retinal + NADPH + H+ Homo sapiens involved in the regeneration of bleached visual pigments in photoreceptor cells, involved in retinol metabolism outside of photoreceptor cells all-trans-retinol + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.300 Homo sapiens O75911
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.300 photoreceptor cone photoreceptor cell Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.300 all-trans-retinal + NAD(P)H + H+
-
 Homo sapiens all-trans-retinol + NAD(P)+
-
 ?
1.1.1.300 all-trans-retinal + NAD(P)H + H+
-
 Homo sapiens all-trans-retinol + NAD(P)+
-
 r
1.1.1.300 all-trans-retinal + NADPH + H+
-
 Homo sapiens all-trans-retinol + NADP+
-
 r
1.1.1.300 all-trans-retinal + NADPH + H+ involved in the regeneration of bleached visual pigments in photoreceptor cells, involved in retinol metabolism outside of photoreceptor cells Homo sapiens all-trans-retinol + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.300 all-trans-retinol dehydrogenase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.300 NADPH
-
 Homo sapiens