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Literature summary extracted from

  • Ghraf, R.; Raible, M.; Schriefers, H.
    11beta- und 17beta-Hydroxysteroid-dehydrogenase-Aktivitäten der Rattenleber (1973), Hoppe-Seyler's Z. Physiol. Chem., 354, 299-305.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.239 testosterone + NAD+ Rattus norvegicus
-
 androst-4-ene-3,17-dione + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.239 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.239 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.239 additional information
-
 0.186 micromol min/g liver, microsomes, substrate testosterone, coenzyme NAD+ Rattus norvegicus
1.1.1.239 additional information
-
 0.086 micromol min/g liver, microsomes, substrate testosterone, coenzyme NADP+ Rattus norvegicus
1.1.1.239 additional information
-
 0.1556 micromol min/g liver, microsomes, substrate 5alpha-dihydrotestosterone, coenzyme NAD+ Rattus norvegicus
1.1.1.239 additional information
-
 0.046 micromol min/g liver, microsomes, substrate 5alpha-dihydrotestosterone, coenzyme NADP+ Rattus norvegicus
1.1.1.239 additional information
-
 0.388 micromol min/g liver, microsomes, substrate 5beta-dihydrotestosterone, coenzyme NAD+ Rattus norvegicus
1.1.1.239 additional information
-
 0.144 micromol min/g liver, microsomes, substrate 5beta-dihydrotestosterone, coenzyme NADP+ Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.239 testosterone + NAD+
-
 Rattus norvegicus androst-4-ene-3,17-dione + NADH + H+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.239 NAD+
-
 Rattus norvegicus