Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Den, H.; Robinson, W.G.; Coon, M.J.
    Enzymatic conversion of beta-hydroxypropionate to malonic semialdehyde (1959), J. Biol. Chem., 234, 1666-1671.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.59 0.34
-
 NAD+
-
 Sus scrofa
1.1.1.59 20
-
 3-hydroxypropanoate
-
 Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.59 3-hydroxypropanoate + NAD+ Gallus gallus
-
 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+ Escherichia coli
-
 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+ Sus scrofa
-
 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+ Tetrahymena pyriformis
-
 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+ Propionibacterium freudenreichii subsp. shermanii
-
 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+ Eremothecium ashbyi
-
 3-oxopropanoate + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.59 Eremothecium ashbyi
-
-
-
1.1.1.59 Escherichia coli
-
-
-
1.1.1.59 Gallus gallus
-
-
-
1.1.1.59 Propionibacterium freudenreichii subsp. shermanii
-
-
-
1.1.1.59 Sus scrofa
-
-
-
1.1.1.59 Tetrahymena pyriformis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.59 partially Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.59 heart
-
 Sus scrofa
-
1.1.1.59 kidney
-
 Sus scrofa
-
1.1.1.59 liver
-
 Sus scrofa
-
1.1.1.59 pectoral muscle
-
 Gallus gallus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.59 additional information
-
 1.000, 1 unit defined as 0.001 increase in optical density Gallus gallus
1.1.1.59 additional information
-
 1.000, 1 unit defined as 0.001 increase in optical density Escherichia coli
1.1.1.59 additional information
-
 1.000, 1 unit defined as 0.001 increase in optical density Sus scrofa
1.1.1.59 additional information
-
 1.000, 1 unit defined as 0.001 increase in optical density Tetrahymena pyriformis
1.1.1.59 additional information
-
 1.000, 1 unit defined as 0.001 increase in optical density Propionibacterium freudenreichii subsp. shermanii
1.1.1.59 additional information
-
 1.000, 1 unit defined as 0.001 increase in optical density Eremothecium ashbyi

Storage Stability

EC Number Storage Stability Organism
1.1.1.59 several weeks, frozen Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.59 3-hydroxypropanoate + NAD+
-
 Gallus gallus 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+
-
 Escherichia coli 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+
-
 Sus scrofa 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+
-
 Tetrahymena pyriformis 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+
-
 Propionibacterium freudenreichii subsp. shermanii 3-oxopropanoate + NADH + H+
-
 r
1.1.1.59 3-hydroxypropanoate + NAD+
-
 Eremothecium ashbyi 3-oxopropanoate + NADH + H+
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.59 10
-
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.59 NAD+
-
 Gallus gallus
1.1.1.59 NAD+
-
 Escherichia coli
1.1.1.59 NAD+
-
 Sus scrofa
1.1.1.59 NAD+
-
 Tetrahymena pyriformis
1.1.1.59 NAD+
-
 Propionibacterium freudenreichii subsp. shermanii
1.1.1.59 NAD+
-
 Eremothecium ashbyi