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Literature summary extracted from

  • Dothie, J.M.; Giglio, J.R.; Moore, C.B.; Tayler, S.S.; Hartley, B.S.
    Ribitol dehydrogenase of Klebsiella aerogenes. Sequence and properties of wild-type and mutant strains (1985), Biochem. J., 230, 569-578.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.56 G196P mutant D, increased activity towards xylitol Klebsiella aerogenes

General Stability

EC Number General Stability Organism
1.1.1.56 half life in crude extract at 55°C mutant B: 6 min Klebsiella aerogenes
1.1.1.56 half life in crude extract at 55°C mutant D: 30 min Klebsiella aerogenes
1.1.1.56 half life in crude extract at 55°C wild type: 20 min Klebsiella aerogenes

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.56 Klebsiella aerogenes
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.56 ribitol dehydrogenase A and B Klebsiella aerogenes

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.56 ribitol + NAD+
-
Klebsiella aerogenes D-ribulose + NADH
-
?
1.1.1.56 xylitol + NAD+ mutants have increased xylitol activity Klebsiella aerogenes D-xylulose + NADH + H+
-
?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.56 ribitol dehydrogenase A wild type Klebsiella aerogenes
1.1.1.56 ribitol dehydrogenase B mutant enzyme with different properties Klebsiella aerogenes
1.1.1.56 ribitol dehydrogenase D mutant enzyme with different properties Klebsiella aerogenes

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.1.1.56 55
-
half-life of mutant B is 6 min, half-life of mutant D is 30 min, half-life of wild-type enzyme is 20 min Klebsiella aerogenes