Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ohno, S.; Nakajin, S.; Shinoda, M.
    Ontogeny of testicular steroid dehydrogenase enzymes in pig (3alpha/beta-, 20alpha- and 20beta-): evidence for two forms of 3alpha/beta-hydroxysteroid dehydrogenase (1992), J. Steroid Biochem. Mol. Biol., 42, 17-21.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.53 17alpha-hydroxyprogesterone + NADPH + H+ Sus scrofa
-
 17alpha,20beta-dihydroxy-4-pregnene-3-one + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.53 Sus scrofa
-
 primary bifunctional enzyme, 3alpha/beta-hydroxysteroid and 20beta-hydroxysteroid dehydrogenase, is replaced during maturation by a secondary 3alpha/beta-hydroxysteroid dehydrogenase without 20beta-hydroxysteroid dehydrogenase activity
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.53 testis
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.53 17alpha-hydroxyprogesterone + NADPH + H+
-
 Sus scrofa 17alpha,20beta-dihydroxy-pregn-4-ene-3-one + NADP+
-
 ?
1.1.1.53 17alpha-hydroxyprogesterone + NADPH + H+
-
 Sus scrofa 17alpha,20beta-dihydroxy-4-pregnene-3-one + NADP+
-
 ?
1.1.1.53 5alpha-androstan-17beta-ol-3-one + NAD(P)H + H+ i.e. 5alpha-dihydrotestosterone Sus scrofa 5alpha-androstan-3alpha,17beta-diol + NAD(P)+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.53 NADH
-
 Sus scrofa
1.1.1.53 NADPH
-
 Sus scrofa