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Literature summary extracted from

  • Kwan, T.K.; Gower, D.B.
    Kinetic studies of 3alpha- and 3beta-hydroxysteroid dehydrogenase in neonatal porcine testis subcellular fractions (1984), Biochem. Soc. Trans., 12, 842-843.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.51 0.068
-
 5alpha-Androst-16-en-3-one microsomal enzyme Sus scrofa
1.1.1.51 0.107
-
 5alpha-Androst-16-en-3-one mitochondrial enzyme Sus scrofa
1.1.1.51 0.176
-
 5alpha-Androst-16-en-3-one cytosolic enzyme Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.51 cytosol 80% of activity Sus scrofa 5829
-
1.1.1.51 microsome
-
 Sus scrofa
-
-
1.1.1.51 mitochondrion
-
 Sus scrofa 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.51 Sus scrofa
-
 Landrace piglet
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.51 testis
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.51 5alpha-androst-16-en-3-one + NADH
-
 Sus scrofa 3beta-hydroxy-5alpha-androst-16-ene + NAD+
-
 ?
1.1.1.51 testosterone + NAD(P)+
-
 Sus scrofa androst-4-en-3,17-dione + NAD(P)H + H+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.51 NAD+
-
 Sus scrofa
1.1.1.51 NADH
-
 Sus scrofa