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Literature summary extracted from

  • Ishida, S.; Ashihara, H.
    Isoenzymes of phosphogluconate dehydrogenase (decarboxylating) from suspension-cultured Cataranthus roseus cells (1993), Phytochemistry, 33, 1307-1311.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.44 D-5-phosphoribosyl-1-diphosphate
-
 Catharanthus roseus
1.1.1.44 NADPH
-
 Catharanthus roseus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.44 0.006
-
 6-phosphogluconate
-
 Daucus carota
1.1.1.44 0.007
-
 6-phosphogluconate
-
 Vigna radiata
1.1.1.44 0.008
-
 NADP+ cytosolic isoenzyme Catharanthus roseus
1.1.1.44 0.011
-
 NADP+
-
 Pisum sativum
1.1.1.44 0.011
-
 NADP+ plastid isoenzyme Catharanthus roseus
1.1.1.44 0.015
-
 6-phosphogluconate cytosolic isoenzyme Catharanthus roseus
1.1.1.44 0.018
-
 6-phosphogluconate plastid isoenzyme Catharanthus roseus
1.1.1.44 0.023
-
 NADP+ plastid isoenzyme Pisum sativum
1.1.1.44 0.098
-
 6-phosphogluconate
-
 Glycine max
1.1.1.44 0.109
-
 6-phosphogluconate plastid isoenzyme Glycine max

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.44 amyloplast
-
 Catharanthus roseus 9501
-
1.1.1.44 cytosol
-
 Spinacia oleracea 5829
-
1.1.1.44 cytosol
-
 Pisum sativum 5829
-
1.1.1.44 cytosol
-
 Ricinus communis 5829
-
1.1.1.44 cytosol
-
 Acer pseudoplatanus 5829
-
1.1.1.44 cytosol
-
 Catharanthus roseus 5829
-
1.1.1.44 plastid
-
 Pisum sativum 9536
-
1.1.1.44 plastid
-
 Ricinus communis 9536
-
1.1.1.44 plastid
-
 Acer pseudoplatanus 9536
-
1.1.1.44 plastid
-
 Catharanthus roseus 9536
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+ Pisum sativum
-
 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Glycine max
-
 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Vigna radiata
-
 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Daucus carota
-
 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Acer pseudoplatanus
-
 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Spinacia oleracea enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Ricinus communis enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Catharanthus roseus enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ Catharanthus roseus B/S enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.44 Acer pseudoplatanus
-
 sycamore cells
-
1.1.1.44 Catharanthus roseus
-
-
-
1.1.1.44 Catharanthus roseus B/S
-
-
-
1.1.1.44 Daucus carota
-
 carrot
-
1.1.1.44 Glycine max
-
 soybean
-
1.1.1.44 Pisum sativum
-
 pea
-
1.1.1.44 Ricinus communis
-
-
-
1.1.1.44 Spinacia oleracea
-
-
-
1.1.1.44 Vigna radiata
-
 black gram, mung bean
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.44 endosperm
-
 Ricinus communis
-
1.1.1.44 endosperm
-
 Acer pseudoplatanus
-
1.1.1.44 leaf
-
 Spinacia oleracea
-
1.1.1.44 leaf
-
 Ricinus communis
-
1.1.1.44 nodule
-
 Glycine max
-
1.1.1.44 root
-
 Pisum sativum
-
1.1.1.44 root
-
 Daucus carota
-
1.1.1.44 root
-
 Acer pseudoplatanus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.44 additional information
-
 plastid isoenzyme 4.8 nkat mg-1 protein, cytosolic isoenzyme 2.5 nkat mg-1 protein Catharanthus roseus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Spinacia oleracea D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Pisum sativum D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Glycine max D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Ricinus communis D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Vigna radiata D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Daucus carota D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Acer pseudoplatanus D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Catharanthus roseus D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Spinacia oleracea D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Ricinus communis D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Catharanthus roseus D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+
-
 Catharanthus roseus B/S D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r
1.1.1.44 6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Catharanthus roseus B/S D-ribulose 5-phosphate + CO2 + NADPH + H+
-
 r