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Literature summary extracted from
- Purification and characterization of a monomeric isocitrate dehydrogenase from Desulfobacter vibrioformis and demonstration of the presence of a monomeric enzyme in other bacteria (1998), FEMS Microbiol. Lett., 160, 75-79.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.42 | 0.0102 | - |
NADP+ | in presence of Mg2+ | Desulfobacter vibrioformis |  |
| 1.1.1.42 | 0.0204 | - |
D,L-isocitrate | in presence of Mg2+ | Desulfobacter vibrioformis | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.42 | Mg2+ | absolute requirement for divalent cations | Desulfobacter vibrioformis | |
| 1.1.1.42 | Mn2+ | absolute requirement for divalent cations | Desulfobacter vibrioformis | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 80000 | - |
1 * 80000, SDS-PAGE | Desulfobacter vibrioformis |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.42 | isocitrate + NADP+ | Desulfobacter vibrioformis | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.42 | Desulfobacter vibrioformis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.42 | - |
Desulfobacter vibrioformis |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 202.2 | - |
- |
Desulfobacter vibrioformis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.42 | isocitrate + NADP+ | - |
Desulfobacter vibrioformis | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.42 | monomer | 1 * 80000, SDS-PAGE | Desulfobacter vibrioformis |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 45 | - |
- |
Desulfobacter vibrioformis |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 8.5 | - |
- |
Desulfobacter vibrioformis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.42 | NADP+ | - |
Desulfobacter vibrioformis | |
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