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Literature summary extracted from
- Purification and characterization of a monomeric isocitrate dehydrogenase with dual coenzyme specificity from the photosynthetic bacterium Rhodomicrobium vannielii (1991), Eur. J. Biochem., 202, 85-93.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.42 | 0.0025 | - |
NADP+ | - |
Rhodomicrobium vannielii |  |
| 1.1.1.42 | 0.77 | - |
NAD+ | - |
Rhodomicrobium vannielii | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 75000 | 80000 | PAGE | Rhodomicrobium vannielii |
| 1.1.1.42 | 80000 | - |
1 * 80000, SDS-PAGE | Rhodomicrobium vannielii |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.42 | isocitrate + NADP+ | Rhodomicrobium vannielii | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.42 | Rhodomicrobium vannielii | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.42 | - |
Rhodomicrobium vannielii |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.42 | 18.5 | - |
NAD+-linked reaction | Rhodomicrobium vannielii |
| 1.1.1.42 | 23 | - |
NADP+-linked reaction | Rhodomicrobium vannielii |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.42 | isocitrate + NAD+ | - |
Rhodomicrobium vannielii | 2-oxoglutarate + CO2 + NADH + H+ | - |
r | |
| 1.1.1.42 | isocitrate + NADP+ | - |
Rhodomicrobium vannielii | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.42 | monomer | 1 * 80000, SDS-PAGE | Rhodomicrobium vannielii |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.42 | NAD+ | - |
Rhodomicrobium vannielii | |
| 1.1.1.42 | NADP+ | - |
Rhodomicrobium vannielii | |
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Release 2023.1 (January 2023)
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