BRENDA - Enzyme Database

NAD-specific isocitrate dehydrogenase from bovine heart. Interaction with Ca2+ chelators

Gabriel, J.L.; Plaut, G.W.E.; Biochem. J. 229, 817-822 (1985)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.1.1.41
2-hydroxyethylamine-N,N-diacetate
-
Bos taurus
1.1.1.41
2-Oxopropane-1,1,3-tricarboxylate
only in presence of ADP
Bos taurus
1.1.1.41
EDTA
-
Bos taurus
1.1.1.41
EGTA
-
Bos taurus
1.1.1.41
NADPH
-
Bos taurus
1.1.1.41
nitrilotriacetate
-
Bos taurus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Bos taurus
-
2-oxoglutarate + CO2 + NADH
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.1.41
Bos taurus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
1.1.1.41
-
Bos taurus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.1.1.41
heart
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
286765
Bos taurus
2-oxoglutarate + CO2 + NADH
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Bos taurus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Bos taurus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.1.1.41
2-hydroxyethylamine-N,N-diacetate
-
Bos taurus
1.1.1.41
2-Oxopropane-1,1,3-tricarboxylate
only in presence of ADP
Bos taurus
1.1.1.41
EDTA
-
Bos taurus
1.1.1.41
EGTA
-
Bos taurus
1.1.1.41
NADPH
-
Bos taurus
1.1.1.41
nitrilotriacetate
-
Bos taurus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Bos taurus
-
2-oxoglutarate + CO2 + NADH
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
1.1.1.41
-
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.1.1.41
heart
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
286765
Bos taurus
2-oxoglutarate + CO2 + NADH
-
-
-
?