Literature summary extracted from

Silinski, J.M.; Colman, R.F.
The kinetics of NAD-linked isocitrate dehydrogenase from calf heart (1974), Biochim. Biophys. Acta, 370, 1-25.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.1.1.41	isocitrate + NAD+	Bos taurus	-	2-oxoglutarate + CO2 + NADH + H+	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.41	Bos taurus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.1.1.41	-	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.41	heart	-	Bos taurus	-

Storage Stability

EC Number	Storage Stability	Organism
1.1.1.41	-90°C, no loss of activity after 6 weeks	Bos taurus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.41	isocitrate + NAD+	-	Bos taurus	2-oxoglutarate + CO2 + NADH + H+	-	?

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
1.1.1.41	22	-	-	Bos taurus

Temperature Range [°C]

EC Number	Temperature Minimum [°C]	Temperature Maximum [°C]	Comment	Organism
1.1.1.41	12	37	-	Bos taurus

pH Range

EC Number	pH Minimum	pH Maximum	Comment	Organism
1.1.1.41	5.5	8.6	-	Bos taurus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.41	NAD+	-	Bos taurus

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Release 2023.1 (January 2023)