BRENDA - Enzyme Database

NADP- und NAD-spezifische dehydrogenase in Hydrogenomas eutropha stamm H 16

Glaeser, H.; Schlegel, H.G.; Arch. Microbiol. 86, 327-337 (1972)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.1.1.41
2-oxoglutarate
-
Cupriavidus necator
1.1.1.41
ATP
-
Cupriavidus necator
1.1.1.41
glyoxylate
with oxaloacetate, concomitantly added
Cupriavidus necator
1.1.1.41
NADH
-
Cupriavidus necator
1.1.1.41
pyruvate
with oxaloacetate, concomitantly added, less effective than glyoxylate + oxaloacetate
Cupriavidus necator
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.1.1.41
0.03
-
D,L-isocitrate
-
Cupriavidus necator
1.1.1.41
0.3
-
NAD+
-
Cupriavidus necator
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Cupriavidus necator
-
2-oxoglutarate + CO2 + NADH
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.1.1.41
Cupriavidus necator
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
1.1.1.41
-
Cupriavidus necator
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.1.1.41
0.9
-
-
Cupriavidus necator
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
286750
Cupriavidus necator
2-oxoglutarate + CO2 + NADH
-
-
-
?
Temperature Stability [°C]
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
1.1.1.41
48
-
-
Cupriavidus necator
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Cupriavidus necator
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.1.1.41
NAD+
-
Cupriavidus necator
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.1.1.41
2-oxoglutarate
-
Cupriavidus necator
1.1.1.41
ATP
-
Cupriavidus necator
1.1.1.41
glyoxylate
with oxaloacetate, concomitantly added
Cupriavidus necator
1.1.1.41
NADH
-
Cupriavidus necator
1.1.1.41
pyruvate
with oxaloacetate, concomitantly added, less effective than glyoxylate + oxaloacetate
Cupriavidus necator
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.1.1.41
0.03
-
D,L-isocitrate
-
Cupriavidus necator
1.1.1.41
0.3
-
NAD+
-
Cupriavidus necator
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.1.1.41
isocitrate + NAD+
Cupriavidus necator
-
2-oxoglutarate + CO2 + NADH
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
1.1.1.41
-
Cupriavidus necator
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.1.1.41
0.9
-
-
Cupriavidus necator
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.1.1.41
isocitrate + NAD+
-
286750
Cupriavidus necator
2-oxoglutarate + CO2 + NADH
-
-
-
?
Temperature Stability [°C] (protein specific)
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
1.1.1.41
48
-
-
Cupriavidus necator