Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Young, N.L.; Saudek, C.D.; Crawford, S.A.; Zuckerbrod, S.L.
    Recovery and activation from hydroxymethylglutaryl coenzyme A reductase from rat small intestine (1982), J. Lipid Res., 23, 257-265.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.34 0.004
-
 (S)-3-hydroxy-3-methylglutaryl-CoA
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.34 3-hydroxy-3-methylglutaryl-CoA + NADPH Rattus norvegicus
-
 (R)-mevalonate + CoA + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.34 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.34
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.34 mucosa
-
 Rattus norvegicus
-
1.1.1.34 small intestine
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.34 (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
-
 Rattus norvegicus mevalonate + CoA + 2 NADP+
-
 r
1.1.1.34 3-hydroxy-3-methylglutaryl-CoA + NADPH
-
 Rattus norvegicus (R)-mevalonate + CoA + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.34 NADPH
-
 Rattus norvegicus