Literature summary extracted from

Hardman, M.J.; Crow, V.L.; Cruickshank, D.S.; Pritchard, G.G.
Kinetics of activation of L-lactate dehydrogenase from Streptococcus lactis by fructose 1,6-bisphosphate (1985), Eur. J. Biochem., 146, 179-183.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.1.1.27	fructose 1,6-diphosphate	L-lactate dehydrogenase form which is activated by fructose 1,6-diphosphate	Lactococcus lactis
1.1.1.27	fructose 1,6-diphosphate	binding of fructose 1,6-diphosphate induces a conformational change in the enzyme, producing a form with reduced protein fluorescence and increased activity towards pyruvate reduction	Lactococcus lactis

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.27	Lactococcus lactis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.27	pyruvate + NADH + H+	-	Lactococcus lactis	(S)-lactate + NAD+	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.27	NADH	coenzyme	Lactococcus lactis

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Release 2023.1 (January 2023)