Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Petrash, J.M.; Tarle, I.; Wilson, D.K.; Quiocho, F.A.
    Aldose reductase catalysis and crystallography (1994), Diabetes, 43, 955-959.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.21 structural model Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.21 zopolrestat
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.21 35800
-
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.21 Homo sapiens
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.1.21 alditol + NAD(P)+ = aldose + NAD(P)H + H+ reaction mechanism Homo sapiens
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.21 alditol + NAD(P)+
-
 Homo sapiens aldose + NAD(P)H
-
 r
1.1.1.21 aldose + NAD(P)H wide specificity Homo sapiens alditol + NAD(P)+
-
 ?
1.1.1.21 D-glucose + NAD(P)H
-
 Homo sapiens sorbitol + NAD(P)+
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.21 monomer 1 * 35800, SDS-PAGE Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.21 NADPH
-
 Homo sapiens