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Literature summary extracted from

  • Ryle, C.M.; Tipton, K.F.
    Kinetic studies with low-KM aldehyde reductase from ox brain (1985), Biochem. J., 227, 621-627.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.21 additional information high ionic strength inhibits the enzyme to a higher extent when NADPH instead of NADH is used as a cofactor Bos taurus
1.1.1.21 NADP+ competitve to NADPH Bos taurus
1.1.1.21 pyrid-3-ylcarbinol
-
 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.21 aldose + NAD(P)H Bos taurus
-
 alditol + NAD(P)+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.21 Bos taurus
-
 ox, low-KM enzyme subtype
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.21 brain ox Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.21 alditol + NAD(P)+
-
 Bos taurus aldose + NAD(P)H
-
 r
1.1.1.21 aldose + NAD(P)H
-
 Bos taurus alditol + NAD(P)+
-
 r
1.1.1.21 pyridine-3-aldehyde + NAD(P)H low-KM enzyme subtype Bos taurus 3-hydroxypyridine + NAD(P)+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.21 NADH
-
 Bos taurus
1.1.1.21 NADP+
-
 Bos taurus