Any feedback?
Literature summary extracted from
- Physical and kinetic properties of homogenous bovine lens aldose reductase (1976), J. Biol. Chem., 251, 2696-2702.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.21 | SO42- | stimulation | Bos taurus |  |
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 1.1.1.21 | extremely labile to freezing and thawing unless Carbowax 100 is included, 10 mg/ml | Bos taurus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.21 | 2'-AMP | - |
Bos taurus | |
| 1.1.1.21 | glyceraldehyde | substrate inhibition | Bos taurus | |
| 1.1.1.21 | NADP+ | - |
Bos taurus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.21 | 37000 | - |
gel filtration | Bos taurus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.21 | aldose + NAD(P)H | Bos taurus | - |
alditol + NAD(P)+ | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.21 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.21 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.21 | lens | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.21 | additional information | - |
- |
Bos taurus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 1.1.1.21 | -60°C, indefinitely | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.21 | alditol + NAD(P)+ | - |
Bos taurus | aldose + NAD(P)H | - |
r | |
| 1.1.1.21 | aldose + NAD(P)H | - |
Bos taurus | alditol + NAD(P)+ | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.21 | monomer | 1 * 37000, SDS-PAGE in presence of 2-mercaptoethanol | Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
