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Literature summary extracted from

  • Peralba, J.M.; Cederlund, E.; Crosas, B.; Moreno, A.; Julia, P.; Martinez, S.E.; Persson, B.; Farr s, J.; Pares, X.; Jornvall, H.
    Structural and enzymatic properties of a gastric NADP(H)-dependent and retinal-active alcohol dehydrogenase (1999), J. Biol. Chem., 274, 26021-26026.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.2 frog stomach ADH cDNA cloned Pelophylax perezi

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.2 0.002
-
 m-nitrobenzaldehyde
-
 Pelophylax perezi
1.1.1.2 0.008
-
 all-trans-retinal
-
 Pelophylax perezi
1.1.1.2 0.009
-
 9-cis-retinal
-
 Pelophylax perezi
1.1.1.2 0.01
-
 octanal
-
 Pelophylax perezi
1.1.1.2 0.012
-
 NADPH m-nitrobenzaldehyde as substrate Pelophylax perezi
1.1.1.2 0.015
-
 13-cis-retinal
-
 Pelophylax perezi
1.1.1.2 0.019
-
 9-cis-retinol
-
 Pelophylax perezi
1.1.1.2 0.02
-
 all-trans-retinol
-
 Pelophylax perezi
1.1.1.2 0.03
-
 NADP+
-
 Pelophylax perezi
1.1.1.2 0.04
-
 hexanal
-
 Pelophylax perezi
1.1.1.2 0.06
-
 trans-2-hexenal
-
 Pelophylax perezi
1.1.1.2 0.06
-
 NADP+ ethanol as substrate Pelophylax perezi
1.1.1.2 0.07
-
 pentanal
-
 Pelophylax perezi
1.1.1.2 0.09
-
 Octanol
-
 Pelophylax perezi
1.1.1.2 0.11
-
 Butanal
-
 Pelophylax perezi
1.1.1.2 0.15
-
 Octanol
-
 Pelophylax perezi
1.1.1.2 0.2
-
 NAD+ ethanol as substrate Pelophylax perezi
1.1.1.2 0.22
-
 trans-2-hexenol
-
 Pelophylax perezi
1.1.1.2 0.22
-
 Pentanol at pH 10 Pelophylax perezi
1.1.1.2 0.35
-
 Hexanol
-
 Pelophylax perezi
1.1.1.2 0.52
-
 NADH m-nitrobenzaldehyde as substrate Pelophylax perezi
1.1.1.2 0.8
-
 NAD+ octanol as substrate Pelophylax perezi
1.1.1.2 1.1
-
 Pentanol
-
 Pelophylax perezi
1.1.1.2 1.7
-
 butanol at pH 10 Pelophylax perezi
1.1.1.2 7
-
 acetaldehyde
-
 Pelophylax perezi
1.1.1.2 8.2
-
 butanol
-
 Pelophylax perezi
1.1.1.2 70
-
 ethanol
-
 Pelophylax perezi
1.1.1.2 170
-
 2-butanol
-
 Pelophylax perezi
1.1.1.2 600
-
 ethanol
-
 Pelophylax perezi

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.2 44000
-
 2 * 44000, SDS-PAGE Pelophylax perezi
1.1.1.2 80000
-
 gel filtration Pelophylax perezi

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.2 Clostridium beijerinckii
-
-
-
1.1.1.2 Entamoeba histolytica
-
-
-
1.1.1.2 Pelophylax perezi
-
 frog
-
1.1.1.2 Thermoanaerobacter brockii
-
-
-
1.1.1.2 Thermoanaerobacter ethanolicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.2
-
 Pelophylax perezi

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.2 liver
-
 Pelophylax perezi
-
1.1.1.2 stomach
-
 Pelophylax perezi
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.2 (2E)-hex-2-enal + NADPH + H+
-
 Pelophylax perezi (2E)-2-hexen-1-ol + NADP+
-
 r
1.1.1.2 1-octanol + NADP+
-
 Pelophylax perezi octanal + NADPH
-
 r
1.1.1.2 1-pentanol + NADP+
-
 Thermoanaerobacter ethanolicus n-pentanal + NADPH
-
 r
1.1.1.2 1-pentanol + NADP+
-
 Pelophylax perezi n-pentanal + NADPH
-
 r
1.1.1.2 13-cis-retinal + NADPH
-
 Pelophylax perezi 13-cis-retinol + NADP+
-
 ?
1.1.1.2 2-butanol + NADP+
-
 Thermoanaerobacter ethanolicus butan-2-one + NADPH
-
 r
1.1.1.2 2-butanol + NADP+
-
 Thermoanaerobacter brockii butan-2-one + NADPH
-
 r
1.1.1.2 2-butanol + NADP+
-
 Pelophylax perezi butan-2-one + NADPH
-
 r
1.1.1.2 3-nitrobenzaldehyde + NADH + H+
-
 Pelophylax perezi 3-nitrobenzyl alcohol + NAD+
-
 r
1.1.1.2 9-cis-retinal + NADPH
-
 Pelophylax perezi 9-cis-retinol + NADP+
-
 r
1.1.1.2 9-cis-retinol + NADP+
-
 Pelophylax perezi 9-cis-retinal + NADPH
-
 r
1.1.1.2 acetaldehyde + NADPH + H+
-
 Thermoanaerobacter ethanolicus ethanol + NADP+
-
 ?
1.1.1.2 acetaldehyde + NADPH + H+
-
 Pelophylax perezi ethanol + NADP+
-
 ?
1.1.1.2 all-trans-retinal + NADPH + H+
-
 Pelophylax perezi all-trans-retinol + NADP+
-
 r
1.1.1.2 all-trans-retinol + NADP+
-
 Pelophylax perezi all-trans-retinal + NADPH
-
 r
1.1.1.2 ethanol + NAD+
-
 Pelophylax perezi acetaldehyde + NADH + H+
-
 r
1.1.1.2 ethanol + NADP+
-
 Clostridium beijerinckii acetaldehyde + NADPH + H+
-
 r
1.1.1.2 ethanol + NADP+
-
 Thermoanaerobacter ethanolicus acetaldehyde + NADPH + H+
-
 r
1.1.1.2 ethanol + NADP+
-
 Thermoanaerobacter brockii acetaldehyde + NADPH + H+
-
 r
1.1.1.2 ethanol + NADP+
-
 Pelophylax perezi acetaldehyde + NADPH + H+
-
 r
1.1.1.2 hexanal + NADPH + H+
-
 Pelophylax perezi hexanol + NADP+
-
 r
1.1.1.2 m-nitrobenzaldehyde + NADPH
-
 Pelophylax perezi m-nitrobenzylalcohol + NADP+
-
 r
1.1.1.2 n-butanol + NADP+
-
 Thermoanaerobacter ethanolicus butyraldehyde + NADPH
-
 r
1.1.1.2 n-butanol + NADP+
-
 Pelophylax perezi butyraldehyde + NADPH
-
 r
1.1.1.2 n-butyraldehyde + NADPH
-
 Thermoanaerobacter ethanolicus n-butanol + NADP+
-
 r
1.1.1.2 n-butyraldehyde + NADPH
-
 Pelophylax perezi n-butanol + NADP+
-
 r
1.1.1.2 n-hexanol + NADP+
-
 Pelophylax perezi n-hexanal + NADPH
-
 r
1.1.1.2 n-octanal + NADPH + H+
-
 Pelophylax perezi n-octanol + NADP+
-
 r
1.1.1.2 octanol + NAD+
-
 Pelophylax perezi octanal + NADH + H+
-
 r
1.1.1.2 octanol + NADP+
-
 Pelophylax perezi octanal + NADPH + H+
-
 r
1.1.1.2 pentanal + NADPH
-
 Pelophylax perezi pentanol + NADP+
-
 r
1.1.1.2 trans-2-hexenol + NADP+
-
 Pelophylax perezi trans-2-hexenal + NADPH
-
 r

Subunits

EC Number Subunits Comment Organism
1.1.1.2 dimer 2 * 44000, SDS-PAGE Pelophylax perezi