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Literature summary extracted from

  • Finnerty, W.R.
    Primary alcohol dehydrogenases from Acinetobacter (1990), Methods Enzymol., 188, 14-18.
    View publication on PubMed

General Stability

EC Number General Stability Organism
1.1.1.164 highly unstable, more than 50% loss of activity within 24 h Acinetobacter sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.164 rifampicin inhibits enzyme induction in hexadecanol-grown cells, not in cells grown on ethanol, palmitate or hexadecane Acinetobacter sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.164 0.003
-
 hexadecanol growth on ethanol, NAD+ Acinetobacter sp.
1.1.1.164 0.0073
-
 hexadecanol growth on palmitic acid, NAD+ Acinetobacter sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.164 hexadecanal + NADH Acinetobacter sp. inducible 72fold by growth on hexadecanol, also inducible by ethanol, palmitate or hexadecane hexadecanol + NAD+
-
 ?
1.1.1.164 hexadecanal + NADH Acinetobacter sp. HO1-N inducible 72fold by growth on hexadecanol, also inducible by ethanol, palmitate or hexadecane hexadecanol + NAD+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.164 Acinetobacter sp.
-
-
-
1.1.1.164 Acinetobacter sp. HO1-N
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.164 partial Acinetobacter sp.

Storage Stability

EC Number Storage Stability Organism
1.1.1.164 -20°C, Tris-HCl 10 mM, pH 7.8, precipitation at 50% ammonium sulfate saturation, dissolved in 15fold reduced volume Acinetobacter sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.164 hexadecanal + NADH inducible 72fold by growth on hexadecanol, also inducible by ethanol, palmitate or hexadecane Acinetobacter sp. hexadecanol + NAD+
-
 ?
1.1.1.164 hexadecanal + NADH inducible 72fold by growth on hexadecanol, also inducible by ethanol, palmitate or hexadecane Acinetobacter sp. HO1-N hexadecanol + NAD+
-
 ?
1.1.1.164 additional information enzyme is not visible as enzymatically active protein in zymograms Acinetobacter sp. ?
-
 ?
1.1.1.164 additional information enzyme is not visible as enzymatically active protein in zymograms Acinetobacter sp. HO1-N ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.164 NAD+ preference for Acinetobacter sp.