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Literature summary extracted from

  • Amotz-Ben, A.; Avron, M.
    NADP specific dihydroxyacetone reductase from Dunaliella parva (1973), FEBS Lett., 29, 153-155.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.156 0.004
-
 NADPH
-
 Dunaliella parva
1.1.1.156 0.015
-
 NADP+
-
 Dunaliella parva
1.1.1.156 0.8
-
 dihydroxyacetone
-
 Dunaliella parva
1.1.1.156 1400
-
 glycerol
-
 Dunaliella parva

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.156 glycerol + NADP+ Dunaliella parva low affinity for glycerol and high affinity for dihydroxyacetone promotes synthesis and accumulation of glycerol as the major osmotic regulator of the cell dihydroxyacetone + NADPH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.156 Dunaliella parva
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.156 culture condition:dihydroxyacetone-grown cell
-
 Dunaliella parva
-
1.1.1.156 culture condition:glycerol-grown cell
-
 Dunaliella parva
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.156 1,2-ethanediol + NADP+ 0.3% of the activity compared to glycerol Dunaliella parva hydroxyacetaldehyde + NADPH
-
 r
1.1.1.156 1,2-propanediol + NADP+ 10% of the activity compared to glycerol Dunaliella parva hydroxyacetone + NADPH
-
 r
1.1.1.156 2,3-butanediol + NADP+ 12% of the activity compared to glycerol Dunaliella parva 3-hydroxybutan-2-one + NADPH
-
 r
1.1.1.156 dihydroxyacetonephosphate + NADPH very low activity Dunaliella parva glycerol 3-phosphate + NADP+
-
 ?
1.1.1.156 glycerol + NADP+ low affinity for glycerol and high affinity for dihydroxyacetone promotes synthesis and accumulation of glycerol as the major osmotic regulator of the cell Dunaliella parva dihydroxyacetone + NADPH + H+
-
 r
1.1.1.156 iso-erythritol + NADP+ 0.9% of the activity compared to glycerol Dunaliella parva ? + NADPH
-
 r
1.1.1.156 L-glyceraldehyde + NADPH very low activity Dunaliella parva L-glycerol + NADP+
-
 ?
1.1.1.156 L-ribulose + NADPH very low activity Dunaliella parva ? + NADP+
-
 ?
1.1.1.156 meso-erythritol + NADP+ 0.4% of the activity compared to glycerol Dunaliella parva ? + NADPH
-
 r
1.1.1.156 methylglyoxal + NADPH very low activity Dunaliella parva 2-hydroxypropanal + NADP+
-
 ?
1.1.1.156 sedoheptulose + NADPH very low activity Dunaliella parva ? + NADP+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.156 7.5
-
 dihydroxyacetone reduction Dunaliella parva
1.1.1.156 9
-
 glycerol oxidation Dunaliella parva

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.156 NADP+ can not be replaced by NAD+ Dunaliella parva