Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Katoh, S.; Sueoka, T.
    Isomerization of 6-lactoyl tetrahydropterin by sepiapterin reductase (1987), J. Biochem., 101, 275-278.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH Rattus norvegicus
-
 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.153 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.153 erythrocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.153 6-(S)-lactoyl-7,8-dihydropterin + NADPH
-
 Rattus norvegicus 6-(L-erythro-1',2'-dihydroxypropyl)-7,8-dihydropterin + NADP+
-
 ?
1.1.1.153 6-pyruvoyltetrahydropterin + 2 NADPH + 2 H+
-
 Rattus norvegicus L-erythro-tetrahydrobiopterin + 2 NADP+
-
 ?
1.1.1.153 additional information enzyme also catalyzes the isomerization of 6-1'-oxo-2'-hydroxypropyl tetrahydropterin (6-lactoyltetrahydropterin) to 6-1'-hydroxy-2'-oxopropyltetrahydropterin Rattus norvegicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.153 8.6
-
 optimum of isomerization of 6-1'-oxo-2'-hydroxypropyl(6-lactoyltetrahydropterin) to 6-1'-hydroxy-2'-oxopropyltetrahydropterin Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.153 NADPH
-
 Rattus norvegicus