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Literature summary extracted from

  • Krafft, A.E.; Winter, J.; Bokkenheuser, V.D.; Hylemon, P.B.
    Cofactor requirements of steroid-17-20-desmolase and 20alpha-hydroxysteroid dehydrogenase ativities in cell extracts of Clostridium scindens (1987), J. Steroid Biochem., 28, 49-54.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.149 Mn2+ required [Clostridium] scindens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.149 [Clostridium] scindens
-
 human intestinal flora
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.149 11-deoxycortisol + NADH inducer [Clostridium] scindens ? + NAD+
-
 r
1.1.1.149 cortisol + NADH inducer [Clostridium] scindens 20alpha-dihydrocortisol + NAD+
-
 r
1.1.1.149 cortisone + NADH inducer [Clostridium] scindens ? + NAD+
-
 r
1.1.1.149 additional information 17alpha-hydroxyprogesterone inducer but not substrate [Clostridium] scindens ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.149 NAD+
-
 [Clostridium] scindens
1.1.1.149 NADH
-
 [Clostridium] scindens