EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.14 | cysteine | fructose reduction at pH 7.4, inhibits at pH 9.0 | Rattus norvegicus | |
1.1.1.14 | ZnSO4 | 3.5 mM reverses EDTA inhibition | Rattus norvegicus |
EC Number | General Stability | Organism |
---|---|---|
1.1.1.14 | bovine serum albumin stabilizes at 4°C | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.14 | 2,3-Dimercaptopropanol | - |
Rattus norvegicus | |
1.1.1.14 | cysteine | - |
Rattus norvegicus | |
1.1.1.14 | EDTA | at pH 7.4, not at pH 9.0, fructose reduction | Rattus norvegicus | |
1.1.1.14 | iodoacetate | - |
Rattus norvegicus | |
1.1.1.14 | p-hydroxymercuribenzoate | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.14 | 0.28 | - |
D-sorbitol | - |
Rattus norvegicus | |
1.1.1.14 | 0.4 | - |
D-xylitol | - |
Rattus norvegicus | |
1.1.1.14 | 1.3 | - |
D-ribitol | - |
Rattus norvegicus | |
1.1.1.14 | 16 | - |
D-mannitol | - |
Rattus norvegicus | |
1.1.1.14 | 16.7 | - |
D-galactitol | - |
Rattus norvegicus | |
1.1.1.14 | 20 | - |
L-arabitol | - |
Rattus norvegicus | |
1.1.1.14 | 54 | - |
D-ribulose | - |
Rattus norvegicus | |
1.1.1.14 | 77 | - |
D-fructose | - |
Rattus norvegicus | |
1.1.1.14 | 110 | - |
L-sorbose | - |
Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.14 | sorbitol + NAD+ | Rattus norvegicus | - |
D-fructose + NADH | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.14 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.14 | partial | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.14 | brain | - |
Rattus norvegicus | - |
EC Number | Storage Stability | Organism |
---|---|---|
1.1.1.14 | -85°C, good preservation | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.14 | D-fructose + NADH + H+ | - |
Rattus norvegicus | D-sorbitol + NAD+ | - |
? | |
1.1.1.14 | D-galactitol + NAD+ | - |
Rattus norvegicus | D-tagatose + NADH | - |
? | |
1.1.1.14 | D-mannitol + NAD+ | - |
Rattus norvegicus | ? | - |
? | |
1.1.1.14 | D-ribitol + NAD+ | - |
Rattus norvegicus | ? | - |
? | |
1.1.1.14 | D-ribulose + NADH | - |
Rattus norvegicus | ? | - |
? | |
1.1.1.14 | D-sorbitol + NAD+ | - |
Rattus norvegicus | D-fructose + NADH + H+ | - |
? | |
1.1.1.14 | D-xylitol + NAD+ | - |
Rattus norvegicus | ? | - |
? | |
1.1.1.14 | L-arabitol + NAD+ | - |
Rattus norvegicus | ? | - |
? | |
1.1.1.14 | L-sorbose + NADH | - |
Rattus norvegicus | ? | - |
? | |
1.1.1.14 | sorbitol + NAD+ | - |
Rattus norvegicus | D-fructose + NADH | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.1.1.14 | 7.4 | 8 | D-fructose reduction | Rattus norvegicus |
1.1.1.14 | 9 | 10 | sorbitol oxidation | Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
1.1.1.14 | 6 | 9 | at pH 6 about 70% of maximal activity, at pH 9 about 40%, fructose reduction | Rattus norvegicus |
1.1.1.14 | 7.5 | 10 | at pH 7.5 about 70% of maximal activity, at pH 10 about 100%, sorbitol oxidation | Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.14 | NAD+ | - |
Rattus norvegicus | |
1.1.1.14 | NADH | - |
Rattus norvegicus | |
1.1.1.14 | NADP+ | cannot replace NAD+ | Rattus norvegicus | |
1.1.1.14 | NADPH | - |
Rattus norvegicus |