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Literature summary extracted from

  • Strobel, G.A.; Kosuge, T.
    Polyol metabolism in Diplodia viticola Desm. (1965), Arch. Biochem. Biophys., 109, 622-626.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.138 Hg2+ 90% inhibition of D-mannitol oxidation at 1 mM Diplodia viticola Desm.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.138 0.082
-
 NADP+
-
 Diplodia viticola Desm.
1.1.1.138 128
-
 D-mannitol
-
 Diplodia viticola Desm.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.138 D-fructose + NADPH Diplodia viticola Desm.
-
 D-mannitol + NADP+
-
 r
1.1.1.138 D-mannitol + NADP+ Diplodia viticola Desm. more specific for D-mannitol than for sorbitol or D-arabinitol D-fructose + NADPH + H+
-
 r
1.1.1.138 D-mannitol + NADP+ Diplodia viticola Desm. involved in the mannitol cycle, important for NADPH regeneration D-fructose + NADPH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.138 Diplodia viticola Desm.
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.138 partial Diplodia viticola Desm.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.138 mycelium
-
 Diplodia viticola Desm.
-

Storage Stability

EC Number Storage Stability Organism
1.1.1.138 4°C, no loss of activity within 1 month Diplodia viticola Desm.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.138 D-arabinitol + NADP+
-
 Diplodia viticola Desm. D-xylulose + NADPH + H+
-
 r
1.1.1.138 D-fructose + NADPH
-
 Diplodia viticola Desm. D-mannitol + NADP+
-
 r
1.1.1.138 D-mannitol + NADP+ more specific for D-mannitol than for sorbitol or D-arabinitol Diplodia viticola Desm. D-fructose + NADPH + H+
-
 r
1.1.1.138 D-mannitol + NADP+ involved in the mannitol cycle, important for NADPH regeneration Diplodia viticola Desm. D-fructose + NADPH + H+
-
 r
1.1.1.138 L-sorbitol + NADP+
-
 Diplodia viticola Desm. L-sorbose + NADPH
-
 r

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.1.1.138 50
-
 75% inactivation in 5 min Diplodia viticola Desm.

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.138 NADP+ specific for NADP+ Diplodia viticola Desm.