EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.122 | hydroxylamine | stimulation at high concentrations | Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.122 | 3-Amino-3-deoxy-D-arabinose | - |
Sus scrofa | |
1.1.1.122 | D-arabinose | competitive inhibition of L-fucose oxidation at 2.5 mM | Sus scrofa | |
1.1.1.122 | p-hydroxymercuribenzoate | 20% loss of activity, saturated | Sus scrofa | |
1.1.1.122 | sodium iodoacetate | 20% loss of activity at 20 mM, pH 8.0 | Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.122 | 0.02 | - |
NAD+ | - |
Sus scrofa | |
1.1.1.122 | 0.32 | - |
6-deoxy-L-galactose | - |
Sus scrofa | |
1.1.1.122 | 2.1 | - |
D-arabinose | - |
Sus scrofa | |
1.1.1.122 | 8 | - |
L-galactose | - |
Sus scrofa | |
1.1.1.122 | 8 | - |
3-Amino-3-deoxy-D-arabinose | - |
Sus scrofa | |
1.1.1.122 | 44 | - |
L-Xylose | - |
Sus scrofa | |
1.1.1.122 | 48 | - |
D-Lyxose | - |
Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.122 | 3-amino-3-deoxy-D-arabinose + NAD+ | Sus scrofa | 15% of the activity compared to L-fucose | 3-amino-3-deoxy-D-arabino-1,5-lactone + NADH | - |
? | |
1.1.1.122 | 6-deoxy-L-galactose + NAD+ | Sus scrofa | i.e. L-fucose | 6-deoxy-L-galactono-1,5-lactone + NADH | - |
? | |
1.1.1.122 | D-arabinose + NAD+ | Sus scrofa | 66% of the activity compared to L-fucose | D-arabinono-1,4-lactone + NADH | - |
? | |
1.1.1.122 | D-lyxose + NAD+ | Sus scrofa | 4% of the activity compared to L-fucose | ? + NADH | - |
? | |
1.1.1.122 | L-galactose + NAD+ | Sus scrofa | 13% of the activity compared to L-fucose | L-galactono-1,5-lactone + NADH | - |
? | |
1.1.1.122 | L-xylose + NAD+ | Sus scrofa | 4% of the activity compared to L-fucose | L-xylono-1,5-lactone + NADH | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.122 | Sus scrofa | - |
porcine | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.122 | to homogeneity, chromatography steps, preparative gel electrophoresis | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.122 | liver | - |
Sus scrofa | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.1.1.122 | 433 | - |
purified enzyme | Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.122 | 3-amino-3-deoxy-D-arabinose + NAD+ | 15% of the activity compared to L-fucose | Sus scrofa | 3-amino-3-deoxy-D-arabino-1,5-lactone + NADH | - |
? | |
1.1.1.122 | 3-amino-3-deoxy-D-arabinose + NAD+ | - |
Sus scrofa | 3-amino-3-deoxy-D-arabino-1,5-lactone + NADH + H+ | - |
r | |
1.1.1.122 | 6-deoxy-L-galactose + NAD+ | i.e. L-fucose | Sus scrofa | 6-deoxy-L-galactono-1,5-lactone + NADH | - |
? | |
1.1.1.122 | D-arabinose + NAD+ | 66% of the activity compared to L-fucose | Sus scrofa | D-arabinono-1,4-lactone + NADH | - |
? | |
1.1.1.122 | D-lyxose + NAD+ | 4% of the activity compared to L-fucose | Sus scrofa | ? + NADH | - |
? | |
1.1.1.122 | L-galactose + NAD+ | 13% of the activity compared to L-fucose | Sus scrofa | L-galactono-1,5-lactone + NADH | - |
? | |
1.1.1.122 | L-xylose + NAD+ | 4% of the activity compared to L-fucose | Sus scrofa | L-xylono-1,5-lactone + NADH | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.1.1.122 | 8.7 | - |
- |
Sus scrofa |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.122 | NAD+ | NAD-specific | Sus scrofa |