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Literature summary extracted from

  • Aurich, H.; Kleber, H.P.; Schöpp, W.D.
    An inducible carnitine dehydrogenase from Pseudomonas aeruginosa (1967), Biochim. Biophys. Acta, 139, 505-507.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.108 Hydrazine hydrate 30 mM, 70% inhibition Pseudomonas aeruginosa
1.1.1.108 hydroxylamine 1 mM, complete inhibition Pseudomonas aeruginosa
1.1.1.108 p-chloromercuribenzoate 0.1 mM, complete inhibition Pseudomonas aeruginosa
1.1.1.108 Sodium borate 20 mM, 60% inhibition Pseudomonas aeruginosa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.108 0.042
-
 NAD+
-
 Pseudomonas aeruginosa
1.1.1.108 8.5
-
 L-carnitine
-
 Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.108 (R)-3-hydroxy-4-trimethylaminobutyrate + NAD+ Pseudomonas aeruginosa
-
 3-dehydrocarnitine + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.108 Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.108 (R)-3-hydroxy-4-trimethylaminobutyrate + NAD+
-
 Pseudomonas aeruginosa 3-dehydrocarnitine + NADH + H+
-
 r
1.1.1.108 carnitine + NAD+
-
 Pseudomonas aeruginosa 3-dehydrocarnitine + NADH + H+
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.108 9 9.5
-
 Pseudomonas aeruginosa

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.108 NAD+
-
 Pseudomonas aeruginosa