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Literature summary extracted from

  • Mitchell, M.J.; Crooks, J.R.; Keogh, D.P.; Smith, S.L.
    Ecdysone 20-monooxygenase activity during larval-pupal-adult development of the tabacco hornworm, Manduca sexta (1999), Arch. Insect Biochem. Physiol., 41, 24-32.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.99.22 ecdysone + NADPH + O2 Manduca sexta
-
 20-hydroxyecdysone + NADP+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.22 Manduca sexta
-
 tobacco hornworm
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.99.22 fat body larval Manduca sexta
-
1.14.99.22 midgut larval Manduca sexta
-
1.14.99.22 additional information investigation of enzyme activity in fat body and midgut gland during developmental stages from egg to adult Manduca sexta
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.99.22 additional information
-
-
 Manduca sexta

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.22 alpha-ecdysone + NADPH + O2
-
 Manduca sexta 20-hydroxyecdysone + NADP+ + H2O
-
 ?
1.14.99.22 ecdysone + NADPH + O2
-
 Manduca sexta 20-hydroxyecdysone + NADP+ + H2O
-
 ?