EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.15.4 | CYP11B3 enzyme cDNA cloned into and expressed in COS-7 cells | Rattus norvegicus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.14.15.4 | G59S | mutation in CYP11B3, 5-6fold reduction of activity | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.15.4 | mitochondrion | CYP11B1 in zona fasciculata, CYP11B2 in zona glomerulosa, new CYP11B3 | Rattus norvegicus | 5739 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.15.4 | Rattus norvegicus | - |
neonatal and adult | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.15.4 | adrenal cortex | - |
Rattus norvegicus | - |
1.14.15.4 | brain | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.4 | 11-deoxycorticosterone + reduced adrenal ferredoxin + O2 | 18-/11beta-hydroxylation | Rattus norvegicus | corticosterone + oxidized adrenal ferredoxin + H2O | - |
? |