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Literature summary extracted from

  • Sawamura, A.; Kusunose, E.; Satouchi, K.; Kusunose, M.
    Catalytic properties of rabbit kidney fatty acid omega-hydroxylase cytochrome P-450ka2 (CYP4A7) (1993), Biochim. Biophys. Acta, 1168, 30-36.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.15.3 microsome
-
 Oryctolagus cuniculus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.15.3 n-alkane + NAD(P)H + H+ + O2 Oryctolagus cuniculus
-
 n-alkanol + NAD(P)+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.15.3 Oryctolagus cuniculus
-
 rabbit
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.15.3 renal cortex
-
 Oryctolagus cuniculus
-

Storage Stability

EC Number Storage Stability Organism
1.14.15.3 -30°C, 1 month, loss of 50% activity towards prostaglandin A1 Oryctolagus cuniculus
1.14.15.3 -30°C, 3 years, no loss of activity towards laurate Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.15.3 (n-1)-alkanoate + NADPH + H+ + O2 chain length C10-C16 Oryctolagus cuniculus (omega-1)-hydroxy-n-alkanoate + NADP+ + H2O
-
 ?
1.14.15.3 arachidonic acid + NAD(P)H + H+ + O2
-
 Oryctolagus cuniculus 20-hydroxyicosa-5,8,11,14-tetraenoic acid + NAD(P)+ + H2O
-
 ?
1.14.15.3 fatty acid + NAD(P)H + H+ + O2 chain length C10-C19 Oryctolagus cuniculus omega-hydroxy fatty acid + NAD(P)+ + H2O
-
 ?
1.14.15.3 fatty acid + NAD(P)H + H+ + O2 NADPH-P450 reductase and cytochrome b5 are part of the enzyme system Oryctolagus cuniculus omega-hydroxy fatty acid + NAD(P)+ + H2O
-
 ?
1.14.15.3 lauric acid + NAD(P)H + H+ + O2
-
 Oryctolagus cuniculus 12-hydroxydodecanoic acid + NAD(P)+ + H2O
-
 ?
1.14.15.3 n-alkane + NAD(P)H + H+ + O2
-
 Oryctolagus cuniculus n-alkanol + NAD(P)+ + H2O
-
 ?
1.14.15.3 palmitic acid + NAD(P)H + H+ + O2
-
 Oryctolagus cuniculus 16-hydroxyhexadecanoic acid + NAD(P)+ + H2O
-
 ?
1.14.15.3 prostaglandin A1 + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryctolagus cuniculus ?
-
 ?
1.14.15.3 prostaglandin A2 + NADPH + O2
-
 Oryctolagus cuniculus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.14.15.3 7
-
 Tris buffer Oryctolagus cuniculus
1.14.15.3 8
-
 potassium phosphate buffer Oryctolagus cuniculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.15.3 NADPH
-
 Oryctolagus cuniculus