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Literature summary extracted from
- Modulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase activities by steroids and physiological conditions in hamster (1999), Life Sci., 17, 1585-1593.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.14.23 | microsome | - |
Mesocricetus auratus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.23 | Mesocricetus auratus | - |
sucrose-rich diet reduces enzyme activity to 25% | - |
| 1.14.14.23 | Mesocricetus auratus | - |
golden syrian hamster, 3fold higher activity in males compared to females | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.23 | liver | - |
Mesocricetus auratus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.23 | cholesterol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Mesocricetus auratus | 7alpha-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |  |
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Release 2023.1 (January 2023)
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