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Literature summary extracted from

  • Seeger, M.; Timmis, K.N.; Hofer, B.
    Degradation of chlorobiphenyls catalyzed by the bph-encoded biphenyl-2,3-dioxygenase and biphenyl-2,3-dihydrodiol-2,3-dehydrogenase of Pseudomonas sp. LB400 (1995), FEMS Microbiol. Lett., 133, 259-264.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.12.18 in Escherichia coli, strain BL21(DE3) Pseudomonas sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.56 cis-2,3-dihydro-2,3-dihydroxybiphenyl + ? Pseudomonas sp. polychlorobiphenyl catabolic pathway 2,3-dihydroxybiphenyl + ?
-
 ?
1.3.1.56 cis-2,3-dihydro-2,3-dihydroxybiphenyl + ? Pseudomonas sp. LB400 polychlorobiphenyl catabolic pathway 2,3-dihydroxybiphenyl + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.56 Pseudomonas sp.
-
-
-
1.3.1.56 Pseudomonas sp. LB400
-
-
-
1.14.12.18 Pseudomonas sp.
-
-
-
1.14.12.18 Pseudomonas sp. LB400
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.14.12.18 biphenyl + NADH + H+ + O2 = (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ with chlorinated biphenyls the product is 2,3-dihydroxybiphenyl and HCl Pseudomonas sp.
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.56 cis-2,3-dihydro-2,3-dihydroxybiphenyl + ?
-
 Pseudomonas sp. 2,3-dihydroxybiphenyl + ?
-
 ?
1.3.1.56 cis-2,3-dihydro-2,3-dihydroxybiphenyl + ? polychlorobiphenyl catabolic pathway Pseudomonas sp. 2,3-dihydroxybiphenyl + ?
-
 ?
1.3.1.56 cis-2,3-dihydro-2,3-dihydroxybiphenyl + ?
-
 Pseudomonas sp. LB400 2,3-dihydroxybiphenyl + ?
-
 ?
1.3.1.56 cis-2,3-dihydro-2,3-dihydroxybiphenyl + ? polychlorobiphenyl catabolic pathway Pseudomonas sp. LB400 2,3-dihydroxybiphenyl + ?
-
 ?
1.14.12.18 2,2'-dichlorobiphenyl + NADH + O2
-
 Pseudomonas sp. 5,6-dihydroxy-1-phenylcyclohexa-1,3-diene + 2,3-dihydroxy-2'-chlorobiphenyl + NAD+ + HCl
-
 ?
1.14.12.18 2,2'-dichlorobiphenyl + NADH + O2
-
 Pseudomonas sp. LB400 5,6-dihydroxy-1-phenylcyclohexa-1,3-diene + 2,3-dihydroxy-2'-chlorobiphenyl + NAD+ + HCl
-
 ?
1.14.12.18 2,4'-dichlorobiphenyl + NADH + O2
-
 Pseudomonas sp. 2,3-dihydroxy-4'-chlorobiphenyl + NAD+ + HCl
-
 ?
1.14.12.18 2,4'-dichlorobiphenyl + NADH + O2
-
 Pseudomonas sp. LB400 2,3-dihydroxy-4'-chlorobiphenyl + NAD+ + HCl
-
 ?
1.14.12.18 4-chlorobiphenyl + NADH + O2
-
 Pseudomonas sp. 2',3'-dihydrodiol-4-chlorobiphenyl + NAD+
-
 ?
1.14.12.18 4-chlorobiphenyl + NADH + O2
-
 Pseudomonas sp. LB400 2',3'-dihydrodiol-4-chlorobiphenyl + NAD+
-
 ?