Literature summary extracted from

Jansen, G.A.; Mihalik, S.J.; Watkins, P.A.; Moser, H.W.; Jakobs, C.; Denis, C.; Wanders, R.J.A.
Phytanoyl-CoA hydroxylase is present in human liver, located in peroxisomes, and deficient in Zellweger syndrome: direct, unequivocal evidence for the new, revised pathway of phytanic acid alpha-oxidation in humans (1996), Biochem. Biophys. Res. Commun., 229, 205-210.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.14.11.18	peroxisome	-	Homo sapiens	5777	-

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.14.11.18	Fe2+	requirement	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.11.18	Homo sapiens	-	human	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.11.18	liver	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.14.11.18	0.000041	-	in liver homogenate	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.11.18	phytanoyl-CoA + 2-oxoglutarate + O2	-	Homo sapiens	alpha-hydroxyphytanoyl-CoA + succinate + CO2	-	?

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Release 2023.1 (January 2023)